OPP have closed off a section of Amberley Road (Highway 86) near Bluevale, following a two vehicle crash.
First responders were called to the roadway between McDonald Line and Johnston Line just after 9:00 a.m. Tuesday morning.
Reports say a westbound pickup sideswiped an eastbound transport truck.
According to police, firefighters from Grey Township Fire Department extricated the trapped pickup truck driver, who was airlifted to London hospital with serious injuries.
The driver of the transport was uninjured.
Amberley Road remains closed between McDonald Line and Johnston Line while the investigation continues.